Blueberry muffin baby syndrome. A critical primary sign
of systemic disease

Katarzyna Kaleta; Agata Kłosowicz; Natalia Juśko; Monika Kapińska-Mrowiecka

doi:10.5114/ada.2022.115895

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Letter to the Editor

Blueberry muffin baby syndrome. A critical primary sign of systemic disease

Katarzyna Kaleta

¹

,

Agata Kłosowicz

¹

,

Natalia Juśko

¹

,

Monika Kapińska-Mrowiecka

¹

Department of Dermatology and Venereology, Stefan Zeromski Municipal Hospital, Krakow, Poland

Adv Dermatol Allergol 2022; XXXIX (2): 418-420

DOI: https://doi.org/10.5114/ada.2022.115895

Online publish date: 2022/05/09

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Blueberry muffin baby syndrome is a rare and non-specific clinical presentation in newborns, characterized by the presence of widespread, maculopapular lesions of blue-red or violaceous colour and cohesive consistency [1]. The term “blueberry muffin baby” was initially coined to describe the skin manifestations of congenital rubella during the American epidemic in the 1960s [2, 3]. The presence of skin lesions is secondary to extramedullary hematopoiesis, which can result from intrauterine viral infections (TORCH syndrome), hematologic dyscrasias (twin-to-twin transfusion syndrome, hereditary spherocytosis, haemolytic disease of the newborn) or neoplasms (mastocytosis, histiocytosis, neuroblastoma, rhabdomyosarcoma, leukaemia) [1, 3].

Blueberry muffin baby syndrome. A critical primary sign of systemic disease

Katarzyna Kaleta 1 , Agata Kłosowicz 1 , Natalia Juśko 1 , Monika Kapińska-Mrowiecka 1

Katarzyna Kaleta

¹

,

Agata Kłosowicz

¹

,

Natalia Juśko

¹

,

Monika Kapińska-Mrowiecka

¹