Advances in Dermatology and Allergology
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eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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2/2011
vol. 28
 
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Case Report
Cutaneous-subcutaneous pseudolymphoma after specific immunotherapy with grass-rye pollen-allergen extract containing aluminium hydroxide

Burkhard Kreft
,
Magdalena Bednarczyk
,
Franziska Emmerling
,
Wolfgang Christian Marsch

Post Dermatol Alergol 2011; XXVIII, 2: 134–137
Online publish date: 2011/04/29
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Allergen-specific immunotherapy is an important treatment procedure in IgE-mediated allergic diseases such as allergic rhinitis or insect toxin allergies. A reduction in the clinical reaction to the allergens to which the patient is known to be sensitized is intended by means of antigen-specific influence on the immune system. The allergen-specific immunotherapy can be applied by subcutaneous injections, and for selected allergens by means of sublingual application of the appropriate allergen. Occasionally, the injection of aluminium hydroxide-adsorbed sera induces a usually transient formation of granulomas. We are reporting on a rare case of cutaneous-subcutaneous pseudolymphoma in the injection area of both upper arms, probably induced by subcutaneous allergen-specific immunotherapy.
keywords:

allergen-specific immunotherapy, pseudolymphoma, aluminium hydroxide

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