Inhaled LAMA in the management of asthma: when to add an anticholinergic versus increase inhaled corticosteroid dose

Rafał Pawliczak

doi:10.5114/pja.2025.151349

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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2/2025
vol. 12

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abstract:

Review paper

Inhaled LAMA in the management of asthma: when to add an anticholinergic versus increase inhaled corticosteroid dose

Rafał Pawliczak

¹

Department of Immunopathology, Faculty of Medicine, Medical University of Lodz, Poland

Alergologia Polska – Polish Journal of Allergology 2025; 12, 2: 106–110

DOI: https://doi.org/10.5114/pja.2025.151349

Online publish date: 2025/05/22

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Modern asthma treatment is standardised and based on scientific research data. Nevertheless, even established standards leave considerable room for interpretation and personalised patient management. This paper aims to demonstrate the significance and role of triple therapy (ICS/LABA/LAMA) in asthma, while assisting practising physicians in developing their own therapeutic approaches. The study reviews various aspects of LAMA use in asthma, including pathophysiology, clinical trials, and observational studies. The paper concludes with a proposal for therapeutic management based on current scientific evidence.

keywords:

Inhaled LAMA in the management of asthma: when to add an anticholinergic versus increase inhaled corticosteroid dose

Rafał Pawliczak 1

asthma, treatment, long-acting β2 agonists, long-acting muscarinic antagonists, inhaled corticosteroids, single inhaler triple therapy

Rafał Pawliczak

¹