Advances in Dermatology and Allergology
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eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2003
vol. 20
 
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abstract:

Pemphigus vulgaris in two brothers. Pemphigus IgG4 deposits in hair follicles

Aleksandra Dańczak-Pazdrowska
,
Irena Mariak
,
Marian Dmochowski

Post Derm Alerg 2003: XX, 6: 365-370
Online publish date: 2003/12/16
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We describe two middle-aged brothers, ethnic Poles, with pemphigus vulgaris. Despite the frequent occurrence of T and B cell-mediated autoimmunity to desmogleins, familial pemphigus vulgaris seems to be rare. The detection of pemphigus IgG4 deposits in hair follicles in one brother is yet another suggestion that pemphigus pathology affects not only mucous membranes and skin but also skin appendages.
keywords:

familial pemphigus vulgaris, IgG4, hair follicle


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