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3/2012
vol. 11 abstract:
Review paper
Side effects of tamoxifen and raloxifene therapy
Małgorzata Sobstyl
,
Joanna Tkaczuk-Włach
,
Jacek Sobstyl
,
Grzegorz Jakiel
Przegląd Menopauzalny 2012; 3: 250–253
Online publish date: 2012/07/04
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Tamoxifen and raloxifene belong to a group of selective estrogen receptor modulators (SERMs). Their features and therapeutic effects depend on tissue and hormonal environment in which they are acting. Advantages resulting from selectivity are used in treatment and prevention of breast cancer and osteoporosis. However, side effects of these therapies should not be neglected. The most common negative symptoms of SERMs treatment are endometrial hyperplasia and cancer, hot flashes, night sweats, vaginal atrophy, dyspareunia.
keywords:
tamoxifen, raloxifene, breast cancer, endometrial cancer, hot flashes |
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