Advances in Dermatology and Allergology
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eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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4/2006
vol. 23
 
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abstract:

Special paper
Safety of the treatment with retinoids

Ryszard Żaba

Post Dermatol Alergol 2006; XXIII, 4: 161–174
Online publish date: 2006/09/08
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The purpose of this paper was to evaluate the mechanism of action, efficacy, tolerability and side effects linked to the treatment of some diseases with administration of various retinoids applied locally and/or systemic. Systemic and topical retinoids have been used to treat severe acne vulgaris and many other diseases. Oral retinoids are the most effective class of drugs for many disorders of cornification. Retinoids are also involved in the regulation of diverse biologic functions, among others cellular growth, differentation, alter cellular cohesiveness, and morphogenesis. As with other medications, a risk/benefit ratio should be used to determine whether or not to treat a dermatologic patient with synthetic retinoids.
keywords:

retinoids, biological functions, side effects


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